What Is Ovarian Hypofunction? – Know the Facts!

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Are you depressed due to irregular periods? Do you have severe mood swings? And you cant understand the reason behind it. Do you know they are your ovaries that can slow down their function and show such type of symptoms? And in many young women this problem remained under or misdiagnosed.

Ovarian hypofunction is a condition in which the function of ovaries is reduced and they produce less hormones. This problem leads to infertility in females. The alternate name used for this condition is ovarian insufficiency.

What are the causes of ovarian hypofunction?

The causes of ovarian hypofunction are;

  • genetic factors, such as chromosomal abnormalities.
  • certain autoimmune disorders that change the normal function of the ovaries.
  • Radiation therapy and chemotherapy may also lead to ovarian hypofunction.
  • Cysts in the ovaries
  • Ovarian tumor
  • Unknown factors (idiopathic)
  • Toxins like smoke, chemicals, radiations, pesticides, viruses, may also cause this problem.

What are the symptoms of ovarian hypofunction?

Women those have ovarian hypofunction, suffer from these symptoms that resembles menopause;

  • Irregular or absent periods
  • Mood swings
  • Night sweats
  • Vaginal dryness
  • Hot flashes
  • Infertility

How is ovarian hypofunction diagnosed?

Women having ovarian hypofunction have increased levels of follicle-stimulating hormone (FSH). So a blood test is conducted to check FSH in your body. Some other tests related to autoimmune disorders and thyroid gland are also performed to rule out the cause.

A karyotype test to diagnose abnormalities in your chromosomes is also performed. Your health professional may also want to know If you have a gene associated with fragile X syndrome called FMR1.

What is the treatment of ovarian hypofunction?

Ovarian hypofunction’s symptoms can be treated with estrogen therapy. However, it is difficult to get pregnant with ovarian hypofunction. Usually women with ovarian hypofunction get pregnant with fertilized donor egg.

Calcium and vitamin D supplement therapy is also given to combat the osteoporosis in females fighting with ovarian hypofunction.

What are the risk factors of ovarian hypofunction?

  • Age: The risk increases between ages 35 and 40. Although sometimes it may occur before age 30, primary ovarian insufficiency is possible in younger women and even in teenage girls.
  • Family history: Having a family history of primary ovarian insufficiency increases your risk of developing this disorder.
  • Ovarian surgery: Surgeries involving the ovaries increase the risk of primary ovarian hypofunction.

What are the complications of ovarian hypofunction?

Complications of primary ovarian insufficiency include:

  • Infertility: Inability to get pregnant can be a complication of ovarian hypofunction.
  • Depression or anxiety: The risk of infertility and other complications arising from low estrogen levels causes depression and anxiety in females.
  • Heart disease: Early loss of estrogen might increase your risk of heart disease.
  • Osteoporosis: The hormone estrogen makes bones stronger. Women with low levels of estrogen have an increased risk of developing weak and brittle bones (osteoporosis), that are more likely to break than healthy bones.

Diagnosis of the problem is very important to treat it. So it is necessary to perform proper diagnostic tests and patient should show compliance with doctors instructions to get the proper treatment. You can consult the best gynecologists in Lahore through for further details related to ovarian hypofunction and similar symptoms.


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